Date: July 2025

OpenEvidence Raises $210M Series B at $3.5B Valuation

In July 2025, OpenEvidence raised $210 million in Series B funding at a $3.5 billion valuation. Google Ventures and Kleiner Perkins co-led the round, while Sequoia Capital, Coatue, Conviction, and Thrive also invested. OpenEvidence develops an AI-powered clinical search platform that delivers evidence-based insights directly at the point of care. Moreover, it already partners with NEJM, JAMA, and other publishers. As a result, the system now supports more than 10,000 U.S. hospitals and reaches over 40 % of physicians daily.

Evidence-Based AI Gains Strategic Momentum

This raise demonstrates how AI-powered clinical search has become a central theme in Digital Health. Unlike generic AI assistants, OpenEvidence transforms peer-reviewed evidence into practical answers for clinicians. Consequently, the platform reduces cognitive load, accelerates decision-making, and strengthens trust in AI-driven care. Adoption has grown quickly: usage increased by 2,000 % year-on-year, while monthly consultations now exceed 8.5 million. Therefore, investors view it as a proven model of scaling AI responsibly inside clinical workflows.

Investor and Market Implications

For investors, OpenEvidence highlights growing demand for AI platforms that combine clinical utility with broad adoption. Therefore, funding should prioritize companies that embed trust, evidence, and measurable ROI. Furthermore, strategic opportunities exist in expanding integrations with EHR vendors and payer networks, as well as in licensing content to global markets. As competition intensifies, ventures that secure content exclusivity and maintain credibility will attract both capital and partnerships. Ultimately, those aligning evidence strength with workflow impact will shape the next phase of digital health AI.

Source: https://www.fiercehealthcare.com/ai-and-machine-learning/openevidence-raises-210m-unveils-ai-agents-built-advanced-medical-research | https://www.digitalhealthnews.com/openevidence-raises-210mn-series-b-launches-deepconsult-ai-agent-for-physicians